e-mail: magda.migalska (at) uj.edu.pl
phone: +48 12 664 5200
Research profile and CV: https://www.researchgate.net/profile/Magdalena_Migalska/info
I am interested in evolution of the vertebrate immune system and co-evolution between hosts and pathogens. A recurring theme in my work is Major Histocompatibility Complex (MHC) – group of molecules encoded by extremely polymorphic genes, central for the molecular-level self/non-self recognition and initiation of the adaptive immune response in vertebrates. They are the most widely studied genes that engage in the co-evolutionary dynamics between vertebrate hosts and parasites.
Currently, my main project focuses on trade-offs containing within-individual MHC gene number expansion. In my work, I combine immunological methods (such as immunocytochemistry and flow cytometry) with advanced genetic methods of next-generation, high-throughput amplicon sequencing and sophisticated, bioinformatic analysis of acquired data.