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Dr Magdalena Migalska

Room: 3.2.17

e-mail: magda.migalska (at) uj.edu.pl

phone: +48 12 664 5200                                               

Publications: https://scholar.google.com/citations?user=n0XZ0JEAAAAJ&hl=en

Research profile and CV: https://www.researchgate.net/profile/Magdalena_Migalska/info

 

Research:

I am interested in evolution of the vertebrate immune system and co-evolution between hosts and pathogens. A recurring theme in my work is Major Histocompatibility Complex (MHC) – group of molecules encoded by extremely polymorphic genes, central for the molecular-level self/non-self recognition and  initiation of the adaptive immune response in vertebrates. They are the most widely studied genes that engage in the co-evolutionary dynamics between vertebrate hosts and parasites.

Currently, my main project focuses on trade-offs containing within-individual MHC gene number expansion. In my work, I combine immunological methods (such as immunocytochemistry and flow cytometry) with advanced genetic methods of next-generation, high-throughput amplicon sequencing and sophisticated, bioinformatic analysis of acquired data.